Cannabinoid Encyclopedia

How a study was run

What does Dose mean?

Amount, timing, frequency, and formulation context behind a source-backed row. 1

Simple definition

Dose, in plain English

Amount, timing, frequency, and formulation context behind a source-backed row. 1

Why it matters

How this word is used in cannabinoid research

This word describes how a study was run. It can change whether the study is a close match for the question a reader is asking.

How to read it

Read the definition beside the study details, including dose, route, product, population, and outcome.

Common questions

Questions people ask

What does Dose mean?

Amount, timing, frequency, and formulation context behind a source-backed row.

Why does Dose matter?

This word describes how a study was run. It can change whether the study is a close match for the question a reader is asking.

Is Dose proof that a cannabinoid works?

No. A definition helps explain the language. The related research pages and their sources show what was actually studied.

Sources

Research connected to this term

Definitions explain the word. These links show research records currently connected with it.

  1. 1
    A double-blind, randomized, placebo-controlled study of the safety and effects of CBN with and without CBD on sleep quality preliminary human PubMed 37796540
  2. 2
    A Randomized, Double-Blind, Placebo-Controlled Trial to Assess the Effectiveness and Safety of Melatonin and Three Formulations of Floraworks Proprietary TruCBN for Improving Sleep preliminary human PubMed 39204082
  3. 3
    Cannabinol for acute treatment of insomnia disorder in a randomized placebo-controlled crossover trial preliminary human PubMed 41698831
  4. 4
    A sleepy cannabis constituent: cannabinol and its active metabolite influence sleep architecture in rats preclinical PubMed 39528623
  5. 5
    A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose, Multiple Dose, and Food Effect Trial of the Safety, Tolerability and Pharmacokinetics of Highly Purified Cannabidiol in Healthy Subjects. mechanistic or pharmacological PubMed 30374683
  6. 6
    Cannabidiol for moderate-severe insomnia: a randomized controlled pilot trial of 150 mg of nightly dosing. preliminary human PubMed 38174873
See all 23 connected research sources
  1. 1
    A double-blind, randomized, placebo-controlled study of the safety and effects of CBN with and without CBD on sleep quality preliminary human PubMed 37796540
  2. 2
    A Randomized, Double-Blind, Placebo-Controlled Trial to Assess the Effectiveness and Safety of Melatonin and Three Formulations of Floraworks Proprietary TruCBN for Improving Sleep preliminary human PubMed 39204082
  3. 3
    Cannabinol for acute treatment of insomnia disorder in a randomized placebo-controlled crossover trial preliminary human PubMed 41698831
  4. 4
    A sleepy cannabis constituent: cannabinol and its active metabolite influence sleep architecture in rats preclinical PubMed 39528623
  5. 5
    A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose, Multiple Dose, and Food Effect Trial of the Safety, Tolerability and Pharmacokinetics of Highly Purified Cannabidiol in Healthy Subjects. mechanistic or pharmacological PubMed 30374683
  6. 6
    Cannabidiol for moderate-severe insomnia: a randomized controlled pilot trial of 150 mg of nightly dosing. preliminary human PubMed 38174873
  7. 7
    Modulation of striatal functional connectivity differences in adults with and without autism spectrum disorder in a single-dose randomized trial of cannabidivarin. preliminary human PubMed 34210360
  8. 8
    Effects of cannabidivarin (CBDV) on brain excitation and inhibition systems in adults with and without Autism Spectrum Disorder (ASD): a single dose trial during magnetic resonance spectroscopy. preliminary human PubMed 31748505
  9. 9
    A randomized, double-blind, placebo-controlled, repeated-dose pilot study of the safety, tolerability, and preliminary effects of a cannabidiol (CBD)- and cannabigerol (CBG)-based beverage powder to support recovery from delayed onset muscle soreness (DOMS). preliminary human PubMed 37947792
  10. 10
    A Phase I, Open-Label, Parallel-Group, Single-Dose Trial of the Pharmacokinetics, Safety, and Tolerability of Cannabidiol in Subjects with Mild to Severe Renal Impairment. insufficient PubMed 31802404
  11. 11
    Short-term repeated oral intake of low dose cannabidiol: effects on liver enzyme activity and creatinine concentration during intense exercise. insufficient PubMed 39630203
  12. 12
    Cannabidiol dose dependently reduces alcohol intake in mice via a non-5-HT1A receptor mechanism: Exploration of other potential receptor targets. mechanistic or pharmacological PubMed 40432283
  13. 13
    High-dose cannabidiol for chronic neuropathic pain associated with spinal cord injury: a randomised clinical trial. preliminary human PubMed 42256679
  14. 14
    Cannabis dosing and administration for sleep: a systematic review. insufficient PubMed 36107800
  15. 15
    Randomized, dose-ranging safety trial of cannabidiol in Dravet syndrome. mechanistic or pharmacological PubMed 29540584
  16. 16
    Cognitive and subjective dose-response effects of acute oral Delta 9-tetrahydrocannabinol (THC) in infrequent cannabis users. preliminary human PubMed 12373420
  17. 17
    Practical considerations in medical cannabis administration and dosing. insufficient PubMed 29307505
  18. 18
    The Effects of Dosage-Controlled Cannabis Capsules on Cancer-Related Cachexia and Anorexia Syndrome in Advanced Cancer Patients: Pilot Study. preliminary human PubMed 31595793
  19. 19
    Single dose and chronic oral administration of cannabigerol and cannabigerolic acid-rich hemp extract in fed and fasted dogs: Physiological effect and pharmacokinetic evaluation. mechanistic or pharmacological PubMed 35246858
  20. 20
    Low-Dose Administration of Cannabigerol Attenuates Inflammation and Fibrosis Associated with Methionine/Choline Deficient Diet-Induced NASH Model via Modulation of Cannabinoid Receptor. mechanistic or pharmacological PubMed 36615835
  21. 21
    A Two-Phase, Dose-Ranging, Placebo-Controlled Study of the Safety and Preliminary Test of Acute Effects of Oral Δ8-Tetrahydrocannabivarin in Healthy Participants. preliminary human PubMed 37721990
  22. 22
    The effect of five day dosing with THCV on THC-induced cognitive, psychological and physiological effects in healthy male human volunteers: A placebo-controlled, double-blind, crossover pilot trial. mechanistic or pharmacological PubMed 26577065
  23. 23
    Tetrahydrocannabivarin (THCV) Dose Dependently Blocks or Substitutes for Tetrahydrocannabinol (THC) in a Drug Discrimination Task in Rats. mechanistic or pharmacological PubMed 41008636